Endocrine Abstracts

A 63 year old female was referred to ophthalmology in December 2007 with a 10 day history of redness, itching and watering of her left eye: the eye had congestion, chemosis and mild proptosis, and ocular movements were mildly restricted. There was no reduction in visual acuity. MRI in January reported no intraocular or intraorbital lesion, and an inflammatory cause was sought - possibly thyroid eye disease. She did not improve on pressure lowering treatments but had some impro...

Ectopic insulin secreting tumours are rare and infrequent. Presentation can be with recurrent or constant hypoglycaemia often in older patients with advanced cancer. The mechanism is through: insulin or insulin-like activity (IGF-2)(often termed non-islet cell tumour hypoglycaemia), reduced gluconeogenesis, disruption of glucagon metabolism, or utilisation of glucose by the tumour. Neuroendocrine tumours are recognised as having hypogly...

Ectopic insulin secreting tumours are rare and infrequent. Presentation can be with recurrent or constant hypoglycaemia often in older patients with advanced cancer. The mechanism is through: insulin or insulin-like activity (IGF-2)(often termed non-islet cell tumour hypoglycaemia), reduced gluconeogenesis, disruption of glucagon metabolism, or utilisation of glucose by the tumour. Neuroendocrine tumours are recognised as having hypogly...